Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMCNAM9)

Drug Name
US8710232, 1 Drug Info
Synonyms SCHEMBL4942017; CHEMBL3694266; BDBM120781; US8710232, 1
Cross-matching ID
PubChem CID
11702405
TTD Drug ID
DMCNAM9

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Carboxypeptidase B1 (CPB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
US8710232, 8 DM1MQ7J N. A. N. A. Patented [1]
US8710232, 7 DMCNS9T N. A. N. A. Patented [1]
PMID14640538C3 DMR2L6X Discovery agent N.A. Investigative [2]
PMID19954973C4 DMDYZE5 Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Carboxypeptidase B1 (CPB1) TT4UJX5 CBPB1_HUMAN Inhibitor [1]

References

1 Imidazole derivatives used as TAFIa inhibitors. US8710232.
2 Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithrombotics. J Med Chem. 2003 Dec 4;46(25):5294-7.
3 Oxygenated analogues of UK-396082 as inhibitors of activated thrombin activatable fibrinolysis inhibitor. Bioorg Med Chem Lett. 2010 Jan 1;20(1):92-6.