Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMCNS9T)

Drug Name
US8710232, 7 Drug Info
Synonyms SCHEMBL4947561; CHEMBL3694267; IQZKZQSOVLMDRA-UHFFFAOYSA-N; BDBM120782; US8710232, 7; 3-(6-Aminopyridin-3-yl)-2-(1-cyclopentyl-1H-imidazol-4-yl)propionic acid
Cross-matching ID
PubChem CID
69252172
TTD Drug ID
DMCNS9T

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Carboxypeptidase B1 (CPB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
US8710232, 8 DM1MQ7J N. A. N. A. Patented [1]
US8710232, 1 DMCNAM9 N. A. N. A. Patented [1]
PMID14640538C3 DMR2L6X Discovery agent N.A. Investigative [2]
PMID19954973C4 DMDYZE5 Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
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Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Carboxypeptidase B1 (CPB1) TT4UJX5 CBPB1_HUMAN Inhibitor [1]

References

1 Imidazole derivatives used as TAFIa inhibitors. US8710232.
2 Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithrombotics. J Med Chem. 2003 Dec 4;46(25):5294-7.
3 Oxygenated analogues of UK-396082 as inhibitors of activated thrombin activatable fibrinolysis inhibitor. Bioorg Med Chem Lett. 2010 Jan 1;20(1):92-6.