General Information of Drug (ID: DMCOJM7)

Drug Name
CNTX-6970 Drug Info
Indication
Disease Entry ICD 11 Status REF
Inflammatory pain MG30.42 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMCOJM7

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cenicriviroc DM4V8WF Human immunodeficiency virus infection 1C62 Phase 2 [2]
MLN1202 DM24SOL Metastatic cancer 2D50-2E2Z Phase 2 [3]
BMS-813160 DMKY638 Diabetic nephropathy GB61.Z Phase 2 [4]
CCX-140 DMJ9XCO Diabetic nephropathy GB61.Z Phase 2 [5]
AZD-2423 DMF34UY Chronic obstructive pulmonary disease CA22 Phase 2 [6]
CCX872 DMPVAUT Pancreatic tumour 2C10 Phase 2 [7]
MK-0812 DMRT8K4 Multiple sclerosis 8A40 Phase 2 [8]
Aminoguanidine DMJQDUC Diabetic retinopathy 9B71.0 Phase 1 [9]
TAK-202 DMVYEFZ Melanoma 2C30 Phase 1 [10]
OPL-CCL2-LPM DM3HOUX Arthritis FA20 Phase 1 [11]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
C-C chemokine receptor type 2 (CCR2) TTFZYTO CCR2_HUMAN Antagonist [1]

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Emerging drugs for the treatment of chronic obstructive pulmonary disease. Expert Opin Emerg Drugs. 2006 May;11(2):275-91.
4 A dual CCR2/CCR5 chemokine antagonist, BMS-813160. Expert Opin Ther Pat. 2011 Dec;21(12):1919-24.
5 Present and future in the treatment of diabetic kidney disease. J Diabetes Res. 2015;2015:801348.
6 CA patent application no. 841416, Method of selecting therapeutic indications.
7 Therapeutic use of a clinical stage CCR2 inhibitor, CCX872, in obesity-associated steatohepatitis. The Lancet Volume 383, Supplement 1, 26 February 2014, Pages S78.
8 Assessment of chemokine receptor function on monocytes in whole blood: In vitro and ex vivo evaluations of a CCR2 antagonist. J Immunol Methods. 2010 Jan 31;352(1-2):101-10.
9 Incyte Announces Second Quarter 2005 Financial Results; Reports Positive Phase IIb Results for Reverset in Treatment-Experienced HIV Patients. Incyte Corporation. 2005.
10 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
11 Selective CCR2-targeted macrophage depletion ameliorates experimental mesangioproliferative glomerulonephritis. Clin Exp Immunol. 2009 February; 155(2): 295-303.