Details of the Drug-Related molecule(s) Interaction Atlas

Benzene sulfonamide derivative 3 Drug Info

PMID27172114-Compound-67

Cross-matching ID

PubChem CID

24812126

CAS Number

CAS 1008119-83-2

TTD Drug ID

DMCQLJY

General Information of Drug (ID: DMCQLJY)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

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Drug(s) Targeting Kynurenine 3-hydroxylase (KMO)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GSK065	DMO87YS	Pancreatitis	DC31-DC34	Phase 1	[2]
Isoxazoles and isoxazoline derivative 2	DMKCYSD	N. A.	N. A.	Patented	[1]
Aryl pyrimidine derivative 7	DM8FAW3	N. A.	N. A.	Patented	[1]
Isoxazoles and isoxazoline derivative 1	DMRML9B	N. A.	N. A.	Patented	[1]
Aryl pyrimidine derivative 2	DMU9Y4B	N. A.	N. A.	Patented	[1]
Cyclopropane 1-carboxylic acid derivative 6	DM0OMBW	N. A.	N. A.	Patented	[1]
PMID27172114-Compound-47	DMTIQYD	N. A.	N. A.	Patented	[1]
Isoxazoles and isoxazoline derivative 4	DMW3JZV	N. A.	N. A.	Patented	[1]
Cyclopropane 1-carboxylic acid derivative 2	DMSXB58	N. A.	N. A.	Patented	[1]
Cyclopropane 1-carboxylic acid derivative 9	DMLH9AQ	N. A.	N. A.	Patented	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Inhibitors of the kynurenine pathway as neurotherapeutics: a patent review (2012-2015).Expert Opin Ther Pat. 2016 Jul;26(7):815-32.
2	Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase. Nat Commun. 2017 Jun 12;8:15827.