Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMCRPKS)

Drug Name
CGRP Drug Info
Synonyms Calcitonin gene related peptide; LAB CGRP; CGRP (inhaled, asthma); CGRP (inhaled, asthma), Akela Pharma; Calcitonin gene-related peptide (inhaled, asthma), LAB International
Indication
Disease Entry ICD 11 Status REF
Asthma CA23 Discontinued in Phase 2 [1]
Cross-matching ID
PubChem CID
44134599
TTD Drug ID
DMCRPKS

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Calcitonin gene-related peptide (CALC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eptinezumab DM5LJCI Migraine 8A80 Approved [3]
TEV-48125 DMMTKC6 Migraine 8A80 Phase 3 [4]
ALD-403 DM6RBYT Migraine 8A80 Phase 2 [5]
PF-4427429 DM3427C Migraine 8A80 Phase 1 [6]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calcitonin gene-related peptide (CALC) TTAFORY NOUNIPROTAC Modulator [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022730)
2 Calcitonin gene-related peptide as inflammatory mediator.Pulm Pharmacol Ther.2003;16(3):121-30.
3 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2020
4 TEV-48125 for the preventive treatment of chronic migraine: Efficacy at early time points. Neurology. 2016 Jul 5;87(1):41-8.
5 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
6 Teva Announces Positive Results for TEV-48125 in Phase IIb Chronic Migraine Study Meeting Primary and Secondary Endpoints