Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMD82LM)

Drug Name

AMT-030 Drug Info

Synonyms

AAV gene therapy (AGT, hyperoxaluria), AMT; Adeno-associated virus gene therapy (alanine:glyoxylate aminotransferase, hyperoxaluria), Amsterdam Molecular Therapeutics

Indication

Disease Entry	ICD 11	Status	REF
Hyperoxaluria	5C51.2	Terminated	[1]

Cross-matching ID

TTD Drug ID: DMD82LM

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Alanine glyoxylate aminotransferase (AGXT)	TTF5NVW	SPYA_HUMAN	Modulator	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024084)
2	Adenovirus-associated virus vector-mediated gene transfer in hemophilia B. N Engl J Med. 2011 Dec 22;365(25):2357-65.