General Information of Drug (ID: DMDNRU1)

Drug Name
RNS-60 Drug Info
Indication
Disease Entry ICD 11 Status REF
Asthma CA23 Phase 2 [1]
Multiple sclerosis 8A40 Phase 2 [2]
Amyotrophic lateral sclerosis 8B60.0 Phase 1 [2]
Cross-matching ID
TTD Drug ID
DMDNRU1

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
LAM-003 DMQHWMJ Acute myeloid leukaemia 2A60 Phase 1 [4]
RTA 901 DMA6JME Diabetic neuropathy 8C0Z Phase 1 [5]
ADX-1612 DM86WI0 Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 1 [6]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Heat shock protein 90 (HSP90) TTO7FVG NOUNIPROTAC Modulator [3]

References

1 ClinicalTrials.gov (NCT01714089) Proof of Concept Study Evaluating RNS60 in the Treatment of Relapsing Remitting Multiple Sclerosis. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Clinical pipeline report, company report or official report of Revalesio.
4 LAM-003, a new drug for treatment of tyrosine kinase inhibitor-resistant FLT3-ITD-positive AML. Blood Adv. 2019 Nov 26;3(22):3661-3673.
5 Clinical pipeline report, company report or official report of Reata Pharmaceuticals.
6 Role of Ganetespib, an HSP90 Inhibitor, in Cancer Therapy: From Molecular Mechanisms to Clinical Practice. Int J Mol Sci. 2023 Mar 6;24(5):5014.