Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DME6NMJ)

Drug Name
CYT-0851 Drug Info
Indication
Disease Entry ICD 11 Status REF
B-cell lymphoma 2A86 Phase 1/2 [1]
Solid tumour/cancer 2A00-2F9Z Phase 1/2 [1]
Cross-matching ID
PubChem CID
137542570
TTD Drug ID
DME6NMJ

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting DNA repair protein RAD51 homolog 1 (RAD51)
Drug Name Drug ID Indication ICD 11 Highest Status REF
AMP-PNP DMTOK1D Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNA repair protein RAD51 homolog 1 (RAD51) TTC0G1L RAD51_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT03997968) A Phase 1/2 Study of CYT-0851, an Oral RAD51 Inhibitor, in B-Cell Malignancies and Advanced Solid Tumors. U.S. National Institutes of Health.
2 National Cancer Institute Drug Dictionary (drug name CYT0851).
3 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.