Details of the Drug

General Information of Drug (ID: DME6NMJ)

Drug Name
CYT-0851
Indication
Disease Entry ICD 11 Status REF
B-cell lymphoma 2A86 Phase 1/2 [1]
Solid tumour/cancer 2A00-2F9Z Phase 1/2 [1]
Drug Type
Small molecular drug
Cross-matching ID
TTD ID
DR5VQ1

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNA repair protein RAD51 homolog 1 (RAD51) TTC0G1L RAD51_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03997968) A Phase 1/2 Study of CYT-0851, an Oral RAD51 Inhibitor, in B-Cell Malignancies and Advanced Solid Tumors. U.S. National Institutes of Health.
2 National Cancer Institute Drug Dictionary (drug name CYT0851).
3 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.