General Information of Drug (ID: DMEG4TC)

Drug Name
Stannsoporfin Drug Info
Synonyms SNMPP; Stanate; Sn Mesoporphyrin; Tin mesoporphyrin; Stanate (TN); Stannsoporfin (USAN/INN)
Indication
Disease Entry ICD 11 Status REF
Neonatal hyperbilirubinemia KA87 Phase 2 [1]
Cross-matching ID
PubChem CID
23725028
TTD Drug ID
DMEG4TC

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Drug(s) Targeting Heme oxygenase 1 (HMOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Heme DMGC287 Discovery agent N.A. Investigative [3]
Formic Acid DMNFZC6 Discovery agent N.A. Investigative [4]
2-Propanol, Isopropanol DML5O0H Discovery agent N.A. Investigative [4]
2-Phenylheme DMPIQTE Discovery agent N.A. Investigative [4]
Biliverdine Ix Alpha DMCA0WJ N. A. N. A. Investigative [4]
Verdoheme DM7NRK5 Discovery agent N.A. Investigative [5]
Tin protoporphyrin DMTXJ5S Discovery agent N.A. Investigative [6]
1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone DMOTJWZ Discovery agent N.A. Investigative [3]
12-Phenylheme DMLR2FB Discovery agent N.A. Investigative [4]
⏷ Show the Full List of 9 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Heme oxygenase 1 (HMOX1) TTI6V2A HMOX1_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT01887327) Study Evaluating the Safety and Efficacy of Two Doses of Stannsoporfin in Combination With Phototherapy in Neonates With Hyperbilirubinemia. U.S. National Institutes of Health.
2 Chemoprevention of severe neonatal hyperbilirubinemia. Semin Perinatol. 2004 Oct;28(5):365-8.
3 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
4 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
5 DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.
6 Adenovirus-mediated heme oxygenase-1 gene delivery inhibits injury-induced vascular neointima formation. Circulation. 2001 Nov 27;104(22):2710-5.