Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMEPJ7C)

Drug Name

BI 905677 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Low-density lipoprotein receptor-related protein 5 (LRP5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BI 905681	DMXO3PV	Solid tumour/cancer	2A00-2F9Z	Phase 1	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
LDL receptor related protein-6 (LRP-6)	TTSXOWE	LRP6_HUMAN	Antagonist	[2]
Low-density lipoprotein receptor-related protein 5 (LRP5)	TT7VMG4	LRP5_HUMAN	Antagonist	[2]

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References

1	ClinicalTrials.gov (NCT03604445) This Study Aims to Find and Test a Safe Dose of BI 905677 in Patients With Different Types of Cancer (Solid Tumours). U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Boehringer Ingelheim.