Details of the Drug

General Information of Drug (ID: DMEPJ7C)

Drug Name

BI 905677

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 1	[1]
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Drug Type

Antibody

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
LDL receptor related protein-6 (LRP-6)	TTSXOWE	LRP6_HUMAN	Antagonist	[2]
Low-density lipoprotein receptor-related protein 5 (LRP5)	TT7VMG4	LRP5_HUMAN	Antagonist	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT03604445) This Study Aims to Find and Test a Safe Dose of BI 905677 in Patients With Different Types of Cancer (Solid Tumours). U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Boehringer Ingelheim.