Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMETVFJ)

Drug Name

Omalizumab Drug Info

Synonyms

Xolair; Omalizumab (genetical recombination); Xolair (TN); Omalizumab (USAN/INN); Omalizumab (genetical recombination) (JAN)

Indication

Disease Entry	ICD 11	Status	REF
Asthma	CA23	Approved	[1]
Chronic idiopathic urticaria	EB00.1	Phase 2	[1]

Therapeutic Class

Antiasthmatic Agents

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Immunoglobulin epsilon Fc receptor gamma (FCERG)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Benzylpenicilloyl Polylysine	DMQHM2D	Bacterial infection	1A00-1C4Z	Approved	[3]
Alpha-D-Mannose	DMF5DLW	Discovery agent	N.A.	Investigative	[4]
Fucose	DMAHMSV	N. A.	N. A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Immunoglobulin epsilon Fc receptor gamma (FCERG)	TTDGEC0	FCERG_HUMAN	Modulator	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6890).
2	The potential of biologics for the treatment of asthma. Nat Rev Drug Discov. 2012 Dec;11(12):958-72.
3	Penicillin allergy: anti-penicillin IgE antibodies and immediate hypersensitivity skin reactions employing major and minor determinants of penicillin. Arch Dis Child. 1980 Nov;55(11):857-60.
4	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.