Details of the Drug

General Information of Drug (ID: DMF5DLW)

Drug Name
Alpha-D-Mannose
Synonyms
alpha-D-Mannose; alpha-D-Mannopyranose; alpha-Mannose; alpha-D-Man; UNII-W3F28J9G0W; CHEBI:28729; 7296-15-3; W3F28J9G0W; 3h-mannose; Manalpha1,; 1rdl; 1rin; 29696-75-1; Epitope ID:130701; AC1Q59RC; AC1L4HD7; SCHEMBL76882; CHEMBL365590; WQZGKKKJIJFFOK-PQMKYFCFSA-N; ZINC3860903; FT-0773891; C00936; WURCS=2.0/1,1,0/[a1122h-1a_1-5]/1/
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 180.16
Logarithm of the Partition Coefficient (xlogp) -2.6
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 5
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C6H12O6
IUPAC Name
(2S,3S,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
Canonical SMILES
C([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O
InChI
InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6+/m1/s1
InChIKey
WQZGKKKJIJFFOK-PQMKYFCFSA-N
Cross-matching ID
PubChem CID
185698
ChEBI ID
CHEBI:28729
CAS Number
7296-15-3
TTD ID
D07LUR

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ADAM metallopeptidase 33 (ADAM33) TTQICM2 ADA33_HUMAN Inhibitor [1]
Alpha-galactosidase A (GLA) TTIS03D AGAL_HUMAN Inhibitor [1]
Antithrombin-III (ATIII) TT4QPUL ANT3_HUMAN Inhibitor [1]
Beta-2-glycoprotein 1 (APOH) TT2OUI9 APOH_HUMAN Inhibitor [1]
Cathepsin D (CTSD) TTPT2QI CATD_HUMAN Inhibitor [1]
Cholinesterase (BCHE) TTEB0GD CHLE_HUMAN Inhibitor [1]
Cytotoxic T-lymphocyte protein 4 (CTLA-4) TTI2S1D CTLA4_HUMAN Inhibitor [1]
Deoxyribonuclease I (DNASE1) TTYWGOJ DNAS1_HUMAN Inhibitor [1]
Dipeptidyl peptidase 4 (DPP-4) TTDIGC1 DPP4_HUMAN Inhibitor [1]
Glycoprotein hormones alpha (CGA) TTFC29G GLHA_HUMAN Inhibitor [1]
Heparin cofactor II (SERPIND1) TT8XSKJ HEP2_HUMAN Inhibitor [1]
Immunoglobulin epsilon Fc receptor gamma (FCERG) TTDGEC0 FCERG_HUMAN Inhibitor [1]
Influenza Hemagglutinin (Influ HA) TTF4CAM HEMA_I34A1 Inhibitor [1]
Influenza Neuraminidase (Influ NA) TT50QJ3 NRAM_I33A0 Inhibitor [1]
Insulin-like growth factor I receptor (IGF1R) TTHRID2 IGF1R_HUMAN Inhibitor [1]
Interleukin 6 receptor (IL6R) TT0E5SK IL6RA_HUMAN ; IL6RB_HUMAN Inhibitor [1]
Lactase-phlorizin hydrolase (LCT) TTA0OSE LPH_HUMAN Inhibitor [1]
Lactotransferrin (LTF) TTSZDQU TRFL_HUMAN Inhibitor [1]
Liver carboxylesterase (CES1) TTMF541 EST1_HUMAN Inhibitor [1]
Low-density lipoprotein receptor (LDL-R) TTH0DUS LDLR_HUMAN Inhibitor [1]
Membrane-associated lectin type-C (CD209) TTBXIM9 CD209_HUMAN Inhibitor [1]
Nitric-oxide synthase brain (NOS1) TTZUFI5 NOS1_HUMAN Inhibitor [1]
Phospholipase A2 (PLA2G1B) TT9V5JH PA21B_HUMAN Inhibitor [1]
Prostaglandin G/H synthase 1 (COX-1) TT8NGED PGH1_HUMAN Inhibitor [1]
Reticulon-4 receptor (RTN4R) TTVRZUO RTN4R_HUMAN Inhibitor [1]
Rhodopsin (RHO) TTH0KSX OPSD_HUMAN Inhibitor [1]
T-cell surface antigen CD2 (CD2) TTJDUNO CD2_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.