Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMEWXR2)

• Drug Name: ISIS 101960 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID: TTD Drug ID: DMEWXR2

Molecule-Related Drug Atlas

Drug(s) Targeting MADH6 messenger RNA (MADH6 mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 101987	DMWCK8Q	Discovery agent	N.A.	Investigative	[1]
ISIS 101952	DMS6JD4	Discovery agent	N.A.	Investigative	[1]
ISIS 101983	DMV9PI7	Discovery agent	N.A.	Investigative	[1]
ISIS 101985	DM8CN2M	Discovery agent	N.A.	Investigative	[1]
ISIS 101986	DM5PTQX	Discovery agent	N.A.	Investigative	[1]
ISIS 101996	DM5APGL	Discovery agent	N.A.	Investigative	[1]
ISIS 101998	DMEH6G1	Discovery agent	N.A.	Investigative	[1]
ISIS 101995	DM3EMLB	Discovery agent	N.A.	Investigative	[1]
ISIS 101984	DMYZ5CX	Discovery agent	N.A.	Investigative	[1]
ISIS 101997	DMUZJCD	Discovery agent	N.A.	Investigative	[1]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
MADH6 messenger RNA (MADH6 mRNA)	TTON5JB	SMAD6_HUMAN	Not Available	[1]

References

• [1] US patent application no. 6,277,636, Antisense inhibition of MADH6 expression.