General Information of Drug (ID: DMF2XHZ)

Drug Name
2-(1-dodecyl-1H-indol-3-yl)acetic acid Drug Info
Synonyms CHEMBL521836; 2-(1-dodecyl-1H-indol-3-yl)acetic acid
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
44577010
TTD Drug ID
DMF2XHZ

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
MX-7065 DMP26BW Solid tumour/cancer 2A00-2F9Z Terminated [2]
Ro 20-1724 DM0PSCF Asthma CA23 Terminated [3]
3-isopropyl-4-(phenylthio)naphthalene-1,2-dione DMJZEMB Discovery agent N.A. Investigative [4]
4-(p-toluidino)-3-isopropylnaphthalene-1,2-dione DMQA0EJ Discovery agent N.A. Investigative [4]
1-dodecyl-1H-indole-2,3-dione DMK6BWV Discovery agent N.A. Investigative [1]
3-isopropyl-4-phenylnaphthalene-1,2-dione DMYZCWX Discovery agent N.A. Investigative [4]
NSC-95397 DMX0TAM Discovery agent N.A. Investigative [5]
3-isopropyl-4-(phenylamino)naphthalene-1,2-dione DMHAJ6W Discovery agent N.A. Investigative [4]
3-isopropylnaphthalene-1,2-dione DM46ID2 Discovery agent N.A. Investigative [4]
(E)-2-(1-decyl-2-oxoindolin-3-ylidene)acetic acid DMI146O Discovery agent N.A. Investigative [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
M-phase inducer phosphatase 1 (MPIP1) TTLZS4Q MPIP1_HUMAN Inhibitor [1]

References

1 Design and synthesis of N-alkyl oxindolylidene acetic acids as a new class of potent Cdc25A inhibitors. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3350-3.
2 Handbook of Assay Development in Drug Discovery, Lisa K. Minor, 2013. Page(11).
3 Role of the Cdc25A phosphatase in human breast cancer. J Clin Invest. 2000 Sep;106(6):753-61.
4 Synthesis of miltirone analogues as inhibitors of Cdc25 phosphatases. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1905-8.
5 Structure-based de novo design and biochemical evaluation of novel Cdc25 phosphatase inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4330-4.