Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMF8FK3)

Drug Name

Tisotumab vedotin Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Cervical cancer	2C77.0	Approved	[1]
Ovarian cancer	2C73	Phase 2	[2]
Solid tumour/cancer	2A00-2F9Z	Phase 2	[3]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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Drug(s) Targeting Tissue factor (F3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ALT-836	DMGJ71F	Adult respiratory distress syndrome	CB00	Phase 2	[4]
TT-173	DMSIXG4	Bleeding disorder	GA20-GA21	Phase 2	[5]
MORAb-066	DMTUKW9	Pancreatic cancer	2C10	Phase 1	[6]
D-Pro-Phe-Arg chloromethyl ketone	DMRJQ8X	Discovery agent	N.A.	Investigative	[7]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	FDA Approved Drug Products from FDA Official Website. 2021. Application Number: 761208.
2	ClinicalTrials.gov (NCT03245736) Tisotumab Vedotin Continued Treatment in Patients With Solid Tumors.. U.S. National Institutes of Health.
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4	ImmunoPET of tissue factor expression in triple-negative breast cancer with a radiolabeled antibody Fab fragment. Eur J Nucl Med Mol Imaging. 2015 Jul;42(8):1295-303.
5	TETIS study: evaluation of new topical hemostatic agent TT-173 in tooth extraction. Clin Oral Investig. 2016 Jun;20(5):1055-63.
6	Clinical pipeline report, company report or official report of Morphotek.
7	Novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors. J Med Chem. 2008 Jun 12;51(11):3077-80.