Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMFL5XU)

Drug Name
TPO gene plasmid Drug Info
Synonyms TPO gene plasmid (thrombocytopenia)
Indication
Disease Entry ICD 11 Status REF
Thrombocytopenia 3B64 Investigative [1]
Cross-matching ID
TTD Drug ID
DMFL5XU

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Thyroid peroxidase (TPO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Propylthiouracil DM6D7N8 Hyperthyroidism 5A02 Approved [2]
Carbimazole DMULAI4 Hyperthyroidism 5A02 Approved [3]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Thyroid peroxidase (TPO) TT52XDZ PERT_HUMAN Modulator [1]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2526).
2 Bioinorganic chemistry in thyroid gland: effect of antithyroid drugs on peroxidase-catalyzed oxidation and iodination reactions. Bioinorg Chem Appl. 2006:23214.
3 Diagnosis and treatment of thyrotoxicosis in childhood. A European questionnaire study. Eur J Endocrinol. 1994 Nov;131(5):467-73.