Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMG4RK0)

Drug Name
AAD-2004 Drug Info
Synonyms
AAD-2004; 927685-43-6; UNII-11VWK61J69; 11VWK61J69; 2-Hydroxy-5-((4-(trifluoromethyl)phenethyl)amino)benzoic acid; Benzoic acid, 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)-; Benzoic acid, 2-hydroxy-5-[[2-[4-(trifluoromethyl)phenyl]ethyl]amino]-; UTMVACIBQLDZLP-UHFFFAOYSA-N; SCHEMBL608498; ZINC34885635; AKOS027338686; SB16954; AS-35180; 2-HYDROXY-5-(2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINO)-BENZOIC ACID
Indication
Disease Entry ICD 11 Status REF
Alzheimer disease 8A20 Phase 1 [1]
Cross-matching ID
PubChem CID
16042343
CAS Number
CAS 927685-43-6
TTD Drug ID
DMG4RK0

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Prostaglandin E synthase (PTGES)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Carboxylic acid derivative 1 DM86E2P Angiogenesis disorder BE2Z Patented [2]
Phthalazinone derivative 1 DMNA941 N. A. N. A. Patented [2]
Benzamide derivative 18 DMD7640 N. A. N. A. Patented [2]
Betais-sulfonylamino derivative 1 DMMCDR7 N. A. N. A. Patented [2]
Benzimidazole derivative 13 DMV4DQI N. A. N. A. Patented [2]
Benzamide derivative 16 DMOAXKF N. A. N. A. Patented [2]
Imidazopyridine derivative 5 DMUKBGD N. A. N. A. Patented [2]
Imidazopyridine derivative 6 DMA0V4F N. A. N. A. Patented [2]
PMID28627961-Compound-22 DM36P7T N. A. N. A. Patented [2]
Imidazole benzamide derivative 1 DM0SOKJ Knee pain ME82 Patented [2]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostaglandin E synthase (PTGES) TTYLQ8V PTGES_HUMAN Inhibitor [1]

References

1 Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE2 production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis. J Neurochem. 2012 Sep;122(5):952-61.
2 Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review.Expert Opin Ther Pat. 2017 Sep;27(9):1047-1059.