General Information of Drug (ID: DMG6S8U)

Drug Name
INNO-305 Drug Info
Indication
Disease Entry ICD 11 Status REF
Acute myeloid leukaemia 2A60 Phase 1 [1]
Lung cancer 2C25.0 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMG6S8U

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug(s) Targeting Wilms tumor protein (WT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Combined PR1/WT1 vaccine DMGCTX5 Myeloid leukaemia 2B33.1 Phase 2 [3]
WT1 peptide vaccine DMZ67Q0 leukaemia 2A60-2B33 Phase 2 [4]
WT1-targeted autologous dendritic cell vaccine DMNFZYE Acute myeloid leukaemia 2A60 Phase 2 [5]
FPI-01 DMXOTMP Acute myeloid leukaemia 2A60 Phase 2 [6]
WT-4869 DM3FIMD leukaemia 2A60-2B33 Phase 1/2 [7]
GSK-2130579A DMRXW9P Acute myeloid leukaemia 2A60 Phase 1 [8]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Wilms tumor protein (WT1) TTZ8UT4 WT1_HUMAN Modulator [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023753)
2 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023753)
3 Leukemia-associated antigen-specific T-cell responses following combined PR1 and WT1 peptide vaccination in patients with myeloid malignancies. Blood. 2008 Jan 1;111(1):236-42.
4 Wilms' tumor protein 1 (WT1) peptide vaccination in AML patients: predominant TCR CDR3beta sequence associated with remission in one patient is detectable in other vaccinated patients. Cancer ImmunolImmunother. 2012 Mar;61(3):313-22.
5 ClinicalTrials.gov (NCT01686334) Efficacy Study of Dendritic Cell Vaccination in Patients With Acute Myeloid Leukemia in Remission. U.S. National Institutes of Health.
6 Clinical pipeline report, company report or official report of Formula Pharmaceuticals.
7 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033385)
8 Spoilight on personalized medicine. A pharma matters report, Thomson Reuters, 2012.