General Information of Drug (ID: DMGAPH1)

Drug Name
Befiperide Drug Info
Indication
Disease Entry ICD 11 Status REF
Anxiety disorder 6B00-6B0Z Terminated [1]
Cross-matching ID
PubChem CID
182859
CAS Number
CAS 100927-14-8
TTD Drug ID
DMGAPH1

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug(s) Targeting 5-HT 1 receptor (5HT1R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aryl piperazine derivative 16 DM63XHT N. A. N. A. Patented [3]
Aryl piperazine derivative 14 DMY8NEL N. A. N. A. Patented [3]
Aryl piperazine derivative 15 DMRK4IE N. A. N. A. Patented [3]
RU 24969 DMVW3I9 N. A. N. A. Terminated [4]
FCE-25876 DMR3ZWA Major depressive disorder 6A70.3 Terminated [5]
SRSS-023 DMUGPDB Migraine 8A80 Terminated [6]
Cyanopindolol DMIBLGH Discovery agent N.A. Investigative [7]
⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 1 receptor (5HT1R) TTWT5K7 NOUNIPROTAC Modulator [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000673)
2 Behavioral Pharmacology of 5-ht. Paul Bevan, Paul Bevan Duphar, Alexander R. Cools. 2013. Figure(15.2).
3 5-HT1A receptor ligands and their therapeutic applications: review of new patents.Expert Opin Ther Pat. 2018 Sep;28(9):679-689.
4 Effect of chronic treatment with 5-HT1 agonist (8-OH-DPAT and RU 24969) and antagonist (isapirone) drugs on the behavioural responses of mice to 5-HT1 and 5-HT2 agonists. Br J Pharmacol. 1986 Oct;89(2):377-84.
5 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001389)
6 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019089)
7 The inhibitory effect of serotonin on the spontaneous discharge of suprachiasmatic neurons in hypothalamic slice is mediated by 5-HT(7) receptor. Brain Res Bull. 2001 Mar 1;54(4):395-8.