Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGC970)

Drug Name

AG-013 Drug Info

Synonyms

ActoBiotic (oral mucositis), ActoGenix; TFF-producing Lactococci lactis (mucositis), ActoGenix/VIB/University of Ghent; Trefoil factor producing micro-organisms (TopAct, oral, mucositis), ActoGenix

Indication

Disease Entry	ICD 11	Status	REF
Oral mucositis	DA01.11	Phase 2/3	[1]

Cross-matching ID

TTD Drug ID: DMGC970

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Trefoil factor-1 (TFF1)	TTNOJIZ	TFF1_HUMAN	Modulator	[1]

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References

1	AG013, a mouth rinse formulation of Lactococcus lactis secreting human Trefoil Factor 1, provides a safe and efficacious therapeutic tool for treating oral mucositis. Oral Oncol. 2010 Jul;46(7):564-70.