Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGEYJW)

Drug Name

Pyridine and pyrimidine derivative 1 Drug Info

Synonyms

PMID28447479-Compound-1

Indication

Disease Entry	ICD 11	Status	REF
Fibrosis	GA14-GC01	Patented	[1]
Pain	MG30-MG3Z	Patented	[1]
Solid tumour/cancer	2A00-2F9Z	Patented	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

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Drug(s) Targeting Extracellular lysophospholipase D (E-NPP2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cudetaxestat	DMYLDN9	Idiopathic pulmonary fibrosis	CB03.4	Phase 2	[2]
PMID28447479-Compound-24	DMDOVIZ	N. A.	N. A.	Patented	[1]
Tetra-hydro-carboline derivative 2	DMXTL7V	N. A.	N. A.	Patented	[1]
PMID28447479-Compound-14	DMA91X2	N. A.	N. A.	Patented	[1]
Pyrimidinone derivative 5	DMLFY57	N. A.	N. A.	Patented	[1]
Heteroaromatic ring derivative 3	DMKJL5T	N. A.	N. A.	Patented	[1]
Pyrazolo[3,4-c]pyridine derivative 1	DMQHCDZ	N. A.	N. A.	Patented	[1]
Pyrazole derivative 87	DMGZUAY	N. A.	N. A.	Patented	[1]
Imidazopyrimidinone derivative 1	DMWN17V	N. A.	N. A.	Patented	[1]
PMID28447479-Compound-21	DM8PET6	N. A.	N. A.	Patented	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Extracellular lysophospholipase D (E-NPP2)	TTSCIM2	ENPP2_HUMAN	Inhibitor	[1]

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References

1	Autotaxin inhibitors: a patent review (2012-2016).Expert Opin Ther Pat. 2017 Jul;27(7):815-829.
2	An updated patent review of autotaxin inhibitors (2017-present). Expert Opin Ther Pat. 2021 May;31(5):421-434.