Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGFEPJ)

• Drug Name: Cyclopropyl Drug Info
• Synonyms: Cyclopropyl; Cyclopropyl radical; cyclopropan-1-yl; 2417-82-5; AC1L3VZL; AC1Q1GU5; DTXSID30178882; 16084-EP2281563A1; 16084-EP2275401A1; 16084-EP2316459A1

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 123162
  CAS Number: CAS 2417-82-5
  TTD Drug ID: DMGFEPJ

Molecule-Related Drug Atlas

Drug(s) Targeting Entamoeba Alcohol dehydrogenase 2 (Entamo ADH2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Nicotinamide-Adenine-Dinucleotide	DM9LRKB	N. A.	N. A.	Investigative	[2]
2'-Monophosphoadenosine 5'-Diphosphoribose	DME9S8M	Discovery agent	N.A.	Investigative	[2]
3,5-dichlorosalicylic acid	DMQ45WH	Discovery agent	N.A.	Investigative	[3]
Trifluoroethanol	DMAWTUL	Discovery agent	N.A.	Investigative	[4]
Cyclobutyl	DM35PIJ	Discovery agent	N.A.	Investigative	[1]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Entamoeba Alcohol dehydrogenase 2 (Entamo ADH2)	TTJS7O4	ADH2_ENTHI	Inhibitor	[1]

References

• [1] Entamoeba histolytica alcohol dehydrogenase 2 (EhADH2) as a target for anti-amoebic agents. J Antimicrob Chemother. 2004 Jul;54(1):56-9.
• [2] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [3] Correlation of binding constants and molecular modelling of inhibitors in the active sites of aldose reductase and aldehyde reductase. Bioorg Med Chem. 2009 Feb 1;17(3):1244-50.
• [4] DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.