Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGI58S)

Drug Name

CAR-T cells targeting Lewis-Y Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Discontinued Drug(s)

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Drug(s) Targeting Carbohydrate antigen Lewis-Y (Lewis-Y)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
IGN-311	DMBKZ4R	Solid tumour/cancer	2A00-2F9Z	Terminated	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbohydrate antigen Lewis-Y (Lewis-Y)	TTV75BJ	NOUNIPROTAC	CAR-T-Cell-Therapy	[1]

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References

1	ClinicalTrials.gov (NCT03198052) HER2/Mesothelin/Lewis-Y/PSCA/MUC1/PD-L1/CD80/86-CAR-T Cells Immunotherapy Against Cancers
2	IGN-311. Igeneon. Curr Opin Investig Drugs. 2005 Dec;6(12):1272-9.