General Information of Drug (ID: DMGIJZA)

Drug Name
US8546370, 17 Drug Info
Synonyms SCHEMBL1048459; CHEMBL3642578; BDBM103511; US8546370, 17
Cross-matching ID
PubChem CID
44180013
TTD Drug ID
DMGIJZA

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
US8546370, 102 DMQRO6G N. A. N. A. Patented [1]
US8546370, 11 DM2K6YU N. A. N. A. Patented [1]
aloisine DM7HGX8 Discovery agent N.A. Investigative [2]
K00592a DM1RP5Q Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tyrosine-protein kinase ZAP-70 (ZAP-70) TTUMHT8 ZAP70_HUMAN Inhibitor [1]

References

1 Compounds and compositions as kinase inhibitors. US8546370.
2 Identification of binding specificity-determining features in protein families. J Med Chem. 2012 Mar 8;55(5):1926-39.
3 Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives. Bioorg Med Chem. 2005 Aug 15;13(16):4936-51.