General Information of Drug (ID: DMGOTK4)

Drug Name
Rhumab Beta7 Drug Info
Indication
Disease Entry ICD 11 Status REF
Ulcerative colitis DD71 Phase 3 [1]
Cross-matching ID
TTD Drug ID
DMGOTK4

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Drug(s) Targeting Integrin beta-7 (ITGB7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Vedolizmab DMV3YMX Crohn disease DD70 Approved [3]
AMG-181 DMODJTX Crohn disease DD70 Phase 2 [4]
PTG-100 DMQNRGE Ulcerative colitis DD71 Phase 1 [5]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Integrin beta-7 (ITGB7) TTLT9XQ ITB7_HUMAN Not Available [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026082)
2 A randomised phase I study of etrolizumab (rhuMAb beta7) in moderate to severe ulcerative colitis. Gut. 2013 Aug;62(8):1122-30.
3 Clinical pipeline report, company report or official report of Takeda (2009).
4 Pharmacology of AMG 181, a human anti-alpha4 beta7 antibody that specifically alters trafficking of gut-homing T cells. Br J Pharmacol. 2013 May;169(1):51-68.
5 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)