Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGQ175)

Drug Name

Mapatumumab Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Non-small-cell lung cancer	2C25.Y	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Discontinued Drug(s)

Investigative Drug(s)

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Drug(s) Targeting TRAIL receptor 1 (TRAIL-R1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
RhApo2L/TRAIL	DMIAZJ9	Solid tumour/cancer	2A00-2F9Z	Discontinued in Phase 1/2	[3]
DR-5/DR-4 cross reactive mabs	DMX2TZD	Solid tumour/cancer	2A00-2F9Z	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT00094848) Study of TRM-1 (TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-Hodgkin's Lymphoma (NHL). U.S. National Institutes of Health.
2	National Cancer Institute Drug Dictionary (drug id 486626).
3	Clinical pipeline report, company report or official report of Amgen (2009).
4	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1879).