Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMH7Q4E)

Drug Name

Bimagrumab Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Type 2 diabetes	5A11	Phase 2	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Activin receptor type II (ACVR2)	TTRG4QN	AVR2A_HUMAN; AVR2B_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT03005288) Safety, Pharmacokinetics and Efficacy of Bimagrumab in Overweight and Obese Patients With Type 2 Diabetes. U.S. National Institutes of Health.
2	Effects of bimagrumab, an activin receptor type II inhibitor, on pituitary neurohormonal axes. Clin Endocrinol (Oxf). 2018 Jun;88(6):908-919.