Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMHNYQU)

Drug Name
BDBM50011553 Drug Info
Synonyms CHEMBL3262572; SCHEMBL15587284; BDBM50011553
Cross-matching ID
PubChem CID
90054634
TTD Drug ID
DMHNYQU

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting MEK kinase kinase 4 (MAP4K4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
6-Phenylquinazolin-4-amine DMV5XR7 N. A. N. A. Patented [1]
BDBM50011552 DMW5SD6 N. A. N. A. Patented [1]
PMID23312943C21 DMOJ8QR Discovery agent N.A. Investigative [2]
PMID24673130C26 DM2HVU8 Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
MEK kinase kinase 4 (MAP4K4) TT6NI13 M4K4_HUMAN Inhibitor [1]

References

1 Aminoquinazoline and pyridopyrimidine derivatives. US9592235.
2 Optimization of highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1051-5.
3 Discovery of selective 4-Amino-pyridopyrimidine inhibitors of MAP4K4 using fragment-based lead identification and optimization. J Med Chem. 2014 Apr 24;57(8):3484-93.