Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMHNYWP)

Drug Name

ISIS-GCGR Drug Info

Indication

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Glucagon receptor messenger RNA (GCGR mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
IONIS-GCGR-Rx	DMB4GD9	Type 2 diabetes	5A11	Phase 2	[3]
ISIS 325568	DMEJ4B7	Type-2 diabetes	5A11	Phase 1	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glucagon receptor messenger RNA (GCGR mRNA)	TTLMJSC	GLR_HUMAN	Not Available	[2]

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References

1	ClinicalTrials.gov (NCT01885260) Safety, Tolerability and Efficacy of ISIS-GCGRRx in Type 2 Diabetes. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
3	Clinical pipeline report, company report or official report of Ionis Pharmaceuticals.
4	Design and development of antisense drugs. Expert Opin. Drug Discov. 2008 3(10):1189-1207.