Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMILHMC)

Drug Name
CC8464 Drug Info
Synonyms ASP1807
Indication
Disease Entry ICD 11 Status REF
Neuropathic pain 8E43.0 Phase 1 [1]
Pain MG30-MG3Z Phase 1 [2]
Cross-matching ID
TTD Drug ID
DMILHMC
VARIDT Drug ID
DR01052

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Voltage-gated sodium channel alpha Nav1.7 (SCN9A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
XEN-402 DMR69CG Osteoarthritis FA00-FA05 Phase 2 [3]
PF-05089771 DMD74BJ Chronic pain MG30 Phase 2 [4]
BIIB074 DMLV1ET Bipolar disorder 6A60 Phase 2 [1]
DSP-2230 DM0WTMD Neuropathic pain 8E43.0 Phase 1 [1]
BIIB095 DMUC6EP Pain MG30-MG3Z Phase 1 [1]
GDC0310 DMUNFEP Chronic pain MG30 Phase 1 [2]
DSP-3905 DMYHU24 Neuropathic pain 8E43.0 Phase 1 [1]
PF-05241328 DM2NTBL Pain MG30-MG3Z Phase 1 [5]
DWJ-208 DMQKDJZ Cancer related pain MG30 Phase 1 [1]
RG7893 DM1R4MQ Pain MG30-MG3Z Phase 1 [6]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Voltage-gated sodium channel alpha Nav1.7 (SCN9A) TT4G2JS SCN9A_HUMAN Inhibitor [1]

References

1 Antibodies and venom peptides: new modalities for ion channels. Nat Rev Drug Discov. 2019 May;18(5):339-357.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Treatment of Na(v)1.7-mediated pain in inherited erythromelalgia using a novel sodium channel blocker. Pain. 2012 Jan;153(1):80-5.
4 Primary erythromelalgia: a review. Orphanet J Rare Dis. 2015 Sep 30;10:127.
5 Recent progress in sodium channel modulators for pain. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9.
6 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800041740)