Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMIMPDL)

Drug Name

PCI-34051 Drug Info

Synonyms

PCI-34259; PCI-34260; PCI-40505; PCI-43744; PCI-45159; PCI-47634; PCI-48000; PCI-48001; PCI-48002; PCI-48003; PCI-48004; PCI-48006; PCI-48007; PCI-48008; PCI-48009; PCI-48010; PCI-48011; PCI-48012; PCI-48013; PCI-48018; PCI-48036; PCI-48039; HDAC 8 inhibitors (cancer/inflammation); HDAC 8 inhibitors (cancer/inflammation), Pharmacyclics

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Investigative	[1]

Cross-matching ID

PubChem CID: 24753719
ChEBI ID: CHEBI:94192
CAS Number: CAS 950762-95-5
TTD Drug ID: DMIMPDL

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

Download the Complete Related Drug List

Drug(s) Targeting Histone deacetylase 8 (HDAC8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
NBM-BMX	DM5OWXA	Solid tumour/cancer	2A00-2F9Z	Phase 1	[2]
PMID29671355-Compound-62	DMWRS34	N. A.	N. A.	Patented	[3]
PMID29671355-Compound-43	DMVPMWJ	N. A.	N. A.	Patented	[3]
PMID29671355-Compound-25	DMPV0KZ	N. A.	N. A.	Patented	[3]
PMID29671355-Compound-21	DMPJN0M	N. A.	N. A.	Patented	[3]
PMID29671355-Compound-31	DM3H78D	N. A.	N. A.	Patented	[3]
PMID29671355-Compound-56	DM0VBMI	N. A.	N. A.	Patented	[3]
PMID29671355-Compound-67	DM1RPL4	N. A.	N. A.	Patented	[3]
PMID29671355-Compound-23	DMUBOEX	N. A.	N. A.	Patented	[3]
PMID29671355-Compound-44	DM80A3V	N. A.	N. A.	Patented	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Histone deacetylase 8 (HDAC8)	TTT6LFV	HDAC8_HUMAN	Inhibitor	[1]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2619).
2	Clinical pipeline report, company report or official report of NatureWise Biotech & Medicals.
3	HDAC inhibitors: a 2013-2017 patent survey.Expert Opin Ther Pat. 2018 Apr 19:1-17.