General Information of Drug (ID: DMIN60B)

Drug Name
N-(pyridin-3-ylmethyl)aniline Drug Info
Synonyms
N-(pyridin-3-ylmethyl)aniline; Phenyl-pyridin-3-ylmethyl-amine; 73570-11-3; phenylpyridin-3-ylmethylamine; CHEMBL264669; N-((pyridine-3-yl)methyl)benzeneamine; BAS 06103406; 3ftv; 3ftw; 11X; 3-anilinomethylpyridine; AC1LLDK0; n-(3-pyridylmethyl)aniline; phenyl(3-pyridylmethyl)amine; 3-(phenylaminomethyl)pyridine; MLS000527027; SCHEMBL523753; BJXLHKJBRORJJJ-UHFFFAOYSA-N; N-[(pyridin-3-yl)methyl]aniline; MolPort-002-003-387; ZINC798246; HMS3604C11; HMS2177I23; N-(pyridin-3-ylmethyl)benzenamine; HMS1684G18
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
1082702
TTD Drug ID
DMIN60B

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bestatin DM8L9D4 Acute myeloid leukaemia 2A60 Approved [2]
LYS006 DMI17QR Ulcerative colitis DD71 Phase 2 [3]
Acebilustat DM19UTO Chronic blistering skin disorder ME63.3 Phase 1 [4]
DG051 DM3I0GS Myocardial infarction BA41-BA43 Discontinued in Phase 2 [5]
Acetate Ion DMD08RH Discovery agent N.A. Investigative [6]
JNJ-10392980 DMZH0K8 Discovery agent N.A. Investigative [7]
4-(2-amino-1,3-thiazol-4-yl)phenol DMH5CAQ Discovery agent N.A. Investigative [1]
2-(4-phenoxyphenoxy)ethanamine DM7TBUJ Discovery agent N.A. Investigative [8]
3-(Benzyloxy)Pyridin-2-Amine DM35VEI Discovery agent N.A. Investigative [6]
2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine DMD2QVO Discovery agent N.A. Investigative [9]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Leukotriene A-4 hydrolase (LTA4H) TTXZEAJ LKHA4_HUMAN Inhibitor [1]

References

1 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
2 DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.
3 Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A(4) Hydrolase. J Med Chem. 2021 Feb 25;64(4):1889-1903.
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5 BAY x 1005 attenuates atherosclerosis in apoE/LDLR - double knockout mice. J Physiol Pharmacol. 2007 Sep;58(3):583-8.
6 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
7 Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity. J Med Chem. 2008 Jul 24;51(14):4150-69.
8 Activation and inhibition of leukotriene A4 hydrolase aminopeptidase activity by diphenyl ether and derivatives. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6549-52.
9 Discovery of multitarget inhibitors by combining molecular docking with common pharmacophore matching. J Med Chem. 2008 Dec 25;51(24):7882-8.