General Information of Drug (ID: DMIPNBG)

Drug Name
Nemonaxacin Drug Info
Indication
Disease Entry ICD 11 Status REF
Methicillin-resistant staphylococci infection 1A00-1A09 Phase 3 [1]
Cross-matching ID
TTD Drug ID
DMIPNBG

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [3]
Levofloxacin DMS60RB Acute maxillary sinusitis Approved [3]
Gatifloxacin DMSL679 Acute gonococcal cervicitis Approved [3]
Ozenoxacin DM6KZMG Impetigo 1B72 Approved [4]
Sparfloxacin DMB4HCT Bacterial infection 1A00-1C4Z Approved [3]
Gemifloxacin DMHT34O Bacterial infection 1A00-1C4Z Approved [3]
Besifloxacin DMPHXMI Ocular inflammation 9C61.24 Approved [5]
Finafloxacin DMZEONG Urinary tract infection GC08 Approved [6]
Delafloxacin Meglumine DMVTU5Q Acute bacterial skin infection 1C41 Approved [7]
Moxifloxacin DMU8V4S Bacterial infection 1A00-1C4Z Approved [3]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Staphylococcus Topoisomerase IV (Stap-coc parC) TTIXTO3 PARC_STAAS Modulator [2]

References

1 ClinicalTrials.gov (NCT02205112) A Phase III Study to Evaluate the Efficacy and Safety of Intravenous Infusion of Nemonoxacin in Treating CAP. U.S. National Institutes of Health.
2 In vitro activity of nemonoxacin (TG-873870), a novel non-fluorinated quinolone, against clinical isolates of Staphylococcus aureus, enterococci and Streptococcus pneumoniae with various resistance phenotypes in Taiwan.J Antimicrob Chemother.2009 Dec;64(6):1226-9.
3 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
4 In vitro and in vivo antibacterial activity of T-3912, a novel non-fluorinated topical quinolone. J Antimicrob Chemother. 2002 Mar;49(3):455-65.
5 Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
6 2014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81.
7 2017 FDA drug approvals.Nat Rev Drug Discov. 2018 Feb;17(2):81-85.