Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMIVHDN)

Drug Name
GSK2618960 Drug Info
Indication
Disease Entry ICD 11 Status REF
Multiple sclerosis 8A40 Phase 1 [1]
Sjogren syndrome 4A43.20 Phase 1 [2]
Cross-matching ID
TTD Drug ID
DMIVHDN

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Interleukin-7 (IL7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ASP9801 DMCDMPW Solid tumour/cancer 2A00-2F9Z Phase 1 [4]
GSK3888130? DMKD6IV Multiple sclerosis 8A40 Phase 1 [5]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-7 (IL7) TT8FRMO IL7_HUMAN Modulator [3]

References

1 ClinicalTrials.gov (NCT01808482) A First Time in Human Study Exploring Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK2618960 in Healthy Volunteers and Patients With Relapsing Remitting Multiple Sclerosis (RRMS). U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 ClinicalTrials.gov (NCT02293161) Single Ascending Doses Study of Anti- Interleukin-7 Receptor alpha Monoclonal Antibody (GSK2618960) in Healthy Volunteers. U.S. National Institutes of Health.
4 Clinical pipeline report, company report or official report of Astellas Pharma.
5 Clinical pipeline report, company report or official report of GlaxoSmithKline