Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJ13TR)

Drug Name
N-Carbamoyl-L-Aspartate Drug Info
Synonyms
N-carbamoyl-L-aspartate; N-Carbamoyl-L-aspartic acid; Ureidosuccinate; L-Ureidosuccinic acid; L-Ureidosuccinate; Carbamyl-L-aspartic acid; Carbamoylaspartic acid; N-Carbamoyl-S-aspartic acid; L-N-Carbamoylaspartic acid; Succinic acid, ureido-; Carbamylaspartic acid; Aspartic acid, N-carbamoyl-; UNII-R2521024DK; N-Carbamoylaspartic acid; 2-Ureidobutanedioic acid; 13184-27-5; EINECS 236-134-3; NSC 14983; L-Aspartic acid, N-(aminocarbonyl)-; N-(aminocarbonyl)-L-aspartic acid; R2521024DK; carbamyl-aspartate
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
93072
ChEBI ID
CHEBI:15859
CAS Number
CAS 13184-27-5
TTD Drug ID
DMJ13TR

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Plasmodium Dihydroorotase (Malaria dho)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Orotate DMMB29S Discovery agent N.A. Investigative [2]
Lysine Nz-Carboxylic Acid DMW1YK3 Discovery agent N.A. Investigative [1]
Dihydroorotate DM76BGZ Discovery agent N.A. Investigative [1]
5-Fluoro orotate DMLSC10 Discovery agent N.A. Investigative [2]
5-bromo orotate DM0HCG6 Discovery agent N.A. Investigative [2]
5-iodo orotate DMDKFIO Discovery agent N.A. Investigative [2]
5-methyl orotate DMYNFIP Discovery agent N.A. Investigative [2]
⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Plasmodium Dihydroorotase (Malaria dho) TT09NOX A9CSR1_PLAFA Inhibitor [1]

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2 Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase. Biochem Pharmacol. 1992 Mar 17;43(6):1295-301.