Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJ2763)

Drug Name
IONIS-FB-LRx Drug Info
Indication
Disease Entry ICD 11 Status REF
IgA nephropathy MF8Y Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMJ2763

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
CFB messenger RNA (CFB mRNA) TT3SGK7 CFAB_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT04014335) A Study to Evaluate the Effectiveness and Safety of IONIS-FB-LRx, an Antisense Inhibitor of Complement Factor B, in Adult Participants With Primary IgA Nephropathy. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Ionis Pharmaceuticals.