General Information of Drug (ID: DMJ2763)

Drug Name
IONIS-FB-LRx
Indication
Disease Entry ICD 11 Status REF
IgA nephropathy MF8Y Phase 2 [1]
Drug Type
Antisense oligonucleotide
Cross-matching ID
TTD ID
DQ2Y7L

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
CFB messenger RNA (CFB mRNA) TT3SGK7 CFAB_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04014335) A Study to Evaluate the Effectiveness and Safety of IONIS-FB-LRx, an Antisense Inhibitor of Complement Factor B, in Adult Participants With Primary IgA Nephropathy. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Ionis Pharmaceuticals.