Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJFKSU)

Drug Name

FAICAR Drug Info

Synonyms

Faicar; phosphoribosyl formamidocarboxamide; 5-Formamidoimidazole-4-carboxamide ribotide; 13018-54-7; CHEBI:18381; 5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide; 5'-Phosphoribosyl-5-formamido-4-imidazolecarboxamide; 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide; 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide; 5-(Formylamino)-1-(5-O-Phosphono-Beta-D-Ribofuranosyl)-1h-Imidazole-4-Carboxamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 166760
ChEBI ID: CHEBI:18381
CAS Number: CAS 13018-54-7
TTD Drug ID: DMJFKSU

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Phosphoribosylaminoimidazolecarboxamide formyltransferase (ATIC)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
NSC-88915	DM9WIHJ	Solid tumour/cancer	2A00-2F9Z	Investigative	[2]
NSC-292213	DMNUSKT	Discovery agent	N.A.	Investigative	[2]
NSC-30171	DMFBZEI	Discovery agent	N.A.	Investigative	[2]
NSC-45592	DMQ6GBX	Discovery agent	N.A.	Investigative	[2]
NSC-47729	DMRZJL1	Discovery agent	N.A.	Investigative	[2]
NSC-26699	DM4RPBJ	Discovery agent	N.A.	Investigative	[2]
NSC-37173	DMZFULS	Discovery agent	N.A.	Investigative	[2]
NSC-58046	DMI6WA7	Discovery agent	N.A.	Investigative	[2]
NSC-37031	DMLY6WX	Discovery agent	N.A.	Investigative	[2]
NSC-324572	DMN50OT	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Phosphoribosylaminoimidazolecarboxamide formyltransferase (ATIC)	TT9NVXQ	PUR9_HUMAN	Inhibitor	[1]

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References

1	Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase. J Biol Chem. 2007 Apr 27;282(17):13033-46.
2	Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identif... J Med Chem. 2004 Dec 30;47(27):6681-90.