Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJRQDG)

Drug Name

AG-SPT201 Drug Info

Synonyms

SPT201; S-pantoprazole sodium trihydrate (ulcer), Ahn-Gook; (S)-pantoprazole sodium trihydrate

Indication

Disease Entry	ICD 11	Status	REF
Ulcerative colitis	DD71	Phase 3	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Preclinical Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Gastric H(+)/K(+) ATPase alpha (ATP4A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dexlansoprazole	DM1DBV5	Erosive esophagitis	DA25.0	Approved	[3]
Rabeprazole	DMMZXIW	Bacterial infection	1A00-1C4Z	Approved	[4]
API-023	DM6P93J	Gastroesophageal reflux disease	DA22.Z	Phase 1	[5]
Saliphenylhalamide	DMLMRGH	Solid tumour/cancer	2A00-2F9Z	Preclinical	[5]
PA-10040	DMELTM2	Cardiovascular disease	BA00-BE2Z	Investigative	[5]
CA-50040	DMCLN6M	Colorectal cancer	2B91.Z	Investigative	[5]
ARH-1029	DM8NETP	Helicobacter infection	DA42-DA63	Investigative	[5]
OPC-22575	DMO4WH9	Ulcerative colitis	DD71	Investigative	[5]
CDRI-85/92	DMQDA5W	Stomach ulcer	DA60.Z	Investigative	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT01400945) Efficacy Study of AGSPT201 Tablet to Treat Gastroesophageal Reflux Disease. U.S. National Institutes of Health.
2	Effects of pantoprazole, a novel H+/K+-ATPase inhibitor, on duodenal ulcerogenic and healing responses in rats: a comparative study with omeprazole and lansoprazole. J Gastroenterol Hepatol. 1999 Mar;14(3):251-7.
3	Clinical pipeline report, company report or official report of Takeda (2009).
4	Review article: rabeprazole's tolerability profile in clinical trials. Aliment Pharmacol Ther. 1999 Oct;13 Suppl 5:17-23.
5	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 849).