Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJTU8D)

Drug Name
OGX-427 Drug Info
Indication
Disease Entry ICD 11 Status REF
Bladder cancer 2C94 Phase 2 [1]
Breast cancer 2C60-2C65 Phase 2 [1]
Lung cancer 2C25.0 Phase 2 [1]
Ovarian cancer 2C73 Phase 2 [1]
Prostate cancer 2C82.0 Phase 2 [1]
Therapeutic Class
Antisense
Cross-matching ID
PubChem CID
71710946
CAS Number
CAS 1002331-21-6
TTD Drug ID
DMJTU8D

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Discontinued Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Heat shock protein 27 (HSP27)
Drug Name Drug ID Indication ICD 11 Highest Status REF
NK-1001 DMZMQDN Atrial fibrillation BC81.3 Discontinued in Phase 2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Heat shock protein 27 (HSP27) TTMG98T HSPB3_HUMAN Modulator [2]

References

1 ClinicalTrials.gov (NCT02423590) Study of Gemcitabine/Carboplatin First-line Chemotherapy +/- Apatorsen in Advanced Squamous Cell Lung Cancers. U.S. National Institutes of Health.
2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
3 Novel therapeutic targets in the management of atrial fibrillation. Am J Cardiovasc Drugs. 2014 Dec;14(6):403-21.