Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMK0GTV)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Proteasome beta-9 (PS beta-9)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Peptide analog 21	DMJDFS1	N. A.	N. A.	Patented	[1]
Peptide analog 23	DMDU21R	N. A.	N. A.	Patented	[1]
Peptide analog 41	DM96KXE	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-53	DM6JV1W	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-55	DMY52ZB	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-46	DMP3MXK	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-48	DMVQTR2	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-51	DM0LXT2	N. A.	N. A.	Patented	[1]
Dipeptide analog 1	DM2OTJS	N. A.	N. A.	Patented	[1]
Peptide analog 14	DMN97QF	N. A.	N. A.	Patented	[1]
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Drug(s) Targeting Proteasome beta-5 (PS beta-5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Peptide analog 21	DMJDFS1	N. A.	N. A.	Patented	[1]
Peptide analog 23	DMDU21R	N. A.	N. A.	Patented	[1]
Peptide analog 41	DM96KXE	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-53	DM6JV1W	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-55	DMY52ZB	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-46	DMP3MXK	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-48	DMVQTR2	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-51	DM0LXT2	N. A.	N. A.	Patented	[1]
Peptide analog 37	DMVX71N	N. A.	N. A.	Patented	[1]
Peptide analog 38	DM9FL81	N. A.	N. A.	Patented	[1]
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Drug(s) Targeting Proteasome beta-1 (PS beta-1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Peptide analog 21	DMJDFS1	N. A.	N. A.	Patented	[1]
Peptide analog 23	DMDU21R	N. A.	N. A.	Patented	[1]
Peptide analog 41	DM96KXE	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-53	DM6JV1W	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-55	DMY52ZB	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-46	DMP3MXK	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-48	DMVQTR2	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-51	DM0LXT2	N. A.	N. A.	Patented	[1]
Peptide analog 39	DMYJOTP	N. A.	N. A.	Patented	[1]
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Drug(s) Targeting Proteasome beta-8 (PS beta-8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
M3258	DM6PI5B	Multiple myeloma	2A83	Phase 1	[2]
Peptide analog 21	DMJDFS1	N. A.	N. A.	Patented	[1]
Peptide analog 23	DMDU21R	N. A.	N. A.	Patented	[1]
Peptide analog 41	DM96KXE	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-53	DM6JV1W	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-55	DMY52ZB	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-46	DMP3MXK	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-48	DMVQTR2	N. A.	N. A.	Patented	[1]
PMID29865878-Compound-51	DM0LXT2	N. A.	N. A.	Patented	[1]
Peptide analog 27	DML4XJ2	N. A.	N. A.	Patented	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Proteasome beta-1 (PS beta-1)	TT8EPLT	PSB6_HUMAN	Inhibitor	[1]
Proteasome beta-5 (PS beta-5)	TT68GPI	PSB5_HUMAN	Inhibitor	[1]
Proteasome beta-8 (PS beta-8)	TTEAD9J	PSB8_HUMAN	Inhibitor	[1]
Proteasome beta-9 (PS beta-9)	TTOUSTQ	PSB9_HUMAN	Inhibitor	[1]

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References

1	A patent review of immunoproteasome inhibitors.Expert Opin Ther Pat. 2018 Jul;28(7):517-540.
2	Clinical pipeline report, company report or official report of EMD Serono.