Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DML84CN)

Drug Name

ISIS-CRPRx Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Coronary artery disease	BA80	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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Drug(s) Targeting CRP messenger RNA (CRP mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS-CRP	DMQDUG4	Cardiovascular disease	BA00-BE2Z	Phase 1	[3]
ISIS 133726	DMJ56XU	Discovery agent	N.A.	Investigative	[4]
ISIS 133712	DMDZ3FU	Discovery agent	N.A.	Investigative	[4]
ISIS 140180	DMP9WOZ	Discovery agent	N.A.	Investigative	[4]
ISIS 330031	DM35WFL	Discovery agent	N.A.	Investigative	[4]
ISIS 330012	DMWIVS9	Discovery agent	N.A.	Investigative	[4]
ISIS 329956	DMA96KW	Discovery agent	N.A.	Investigative	[4]
Phosphocholine	DMIZLVW	Discovery agent	N.A.	Investigative	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024563)
2	Antisense oligonucleotides on neurobehavior, respiratory, and cardiovascular function, and hERG channel current studies. J Pharmacol Toxicol Methods. 2014 Jan-Feb;69(1):49-60.
3	Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2009).
4	US patent application no. 7,425,545, Modulation of C-reactive protein expression.
5	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.