Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DML8S0W)

Drug Name
MEDI6570 Drug Info
Indication
Disease Entry ICD 11 Status REF
Cardiovascular disease BA00-BE2Z Phase 2 [1]
Coronary heart disease BA80.Z Phase 2 [1]
Cross-matching ID
TTD Drug ID
DML8S0W

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Discontinued Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Lectin-like oxidized LDL receptor (OLR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
RG7418 DMXRHDL Arteriosclerosis BD40 Discontinued in Phase 1 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Lectin-like oxidized LDL receptor (OLR1) TTKSND3 OLR1_HUMAN Modulator [2]

References

1 ClinicalTrials.gov (NCT04610892) A Phase IIB, Randomized, Double Blinded, Placebo Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of MEDI6570 in Participants With a Prior Myocardial Infarction and Persistent Inflammation. U.S.National Institutes of Health.
2 Clinical pipeline report, company report or official report of AstraZeneca
3 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.