Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMM7S3V)

Drug Name

KB-5359 Drug Info

Synonyms

KB-3495; Selective thyroid hormone agonists (TR STAD, dyslipidemia), Karo Bio

Indication

Disease Entry	ICD 11	Status	REF
Lipid metabolism disorder	5C52.Z	Terminated	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Thyroid hormone receptor (THR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
B7-2/GM-CSF	DM0LKHV	Dementia	6D80-6D86	Phase 1	[3]
Neplanocin A	DMXULGK	Discovery agent	N.A.	Investigative	[4]
GC-14	DMYMGBA	Discovery agent	N.A.	Investigative	[4]
NH-3	DMYAB79	Discovery agent	N.A.	Investigative	[4]
NH-4	DMSUZFO	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Thyroid hormone receptor (THR)	TTQWUPT	NOUNIPROTAC	Modulator	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020270)
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
3	Sobetirome: a case history of bench-to-clinic drug discovery and development. Heart Fail Rev. 2010 Mar;15(2):177-82.
4	Design of thyroid hormone receptor antagonists from first principles. J Steroid Biochem Mol Biol. 2002 Dec;83(1-5):59-73.