Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMMC45B)

Drug Name

Teriparatide Drug Info

Synonyms

Forteo; Forteo (TN); Teriparatide (genetical recombination); Teriparatide (USAN/INN); Teriparatide (genetical recombination) (JAN)

Indication

Disease Entry	ICD 11	Status	REF
Exostosis		Approved	[1]
Myelofibrosis	2A20.2	Approved	[1]
Osteogenesis imperfecta	LD24.K0	Approved	[2]
Osteoporosis	FB83.0	Approved	[1]
Psoriatic disorder	EA90	Discontinued in Phase 2	[3]
Autosomal dominant hypocalcemia	5A50.0Y	Investigative	[1]

Therapeutic Class

Bone Density Conservation Agents

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Discontinued Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Parathyroid hormone (PTH)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
KUR-111	DMZL48U	Bone disease	FC0Z	Phase 2	[5]
Ostabolin-C	DMBVI6E	Osteoporosis	FB83.0	Phase 2	[6]
ABX-PTH	DMDPUK6	Parathyroid disease	5A50-5A5Z	Terminated	[7]
SUN-E3001	DMAM3OH	Osteoporosis	FB83.0	Terminated	[8]
MG-1101	DM710KZ	Discovery agent	N.A.	Investigative	[9]
parathyroid hormone	DMKJY3U	Discovery agent	N.A.	Investigative	[9]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	Teriparatide FDA Label
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4448).
3	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030730)
4	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
5	Company report (Cytos)
6	ZT-031, a cyclized analog of parathyroid hormone(1-31) for the potential treatment of osteoporosis. IDrugs. 2008 Nov;11(11):827-40.
7	Focus on parathyroid carcinoma. International Journal of Surgery Volume 9, Issue 1, 2011, Pages 13-19.
8	Effects of teriparatide [recombinant human parathyroid hormone (1-34)] on cortical bone in postmenopausal women with osteoporosis. J Bone Miner Res. 2003 Mar;18(3):539-43.
9	Daily parathyroid hormone 1-34 replacement therapy for hypoparathyroidism induces marked changes in bone turnover and structure.J Bone Miner Res.2012 Aug;27(8):1811-20.