Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMMC8IG)

Drug Name

2-Deoxy-2fluoro-Glucose Drug Info

Synonyms

2-deoxy-2-fluoro-beta-D-glucopyranose; 2-DEOXY-2FLUORO-GLUCOSE; UNII-41XAV5II5H; 41XAV5II5H; CHEBI:49128; 2-deoxy-2-fluoro-beta-D-glucose; NSC-240588; AC1NRBA5; beta-D-Fludeoxyglucopyranose; SCHEMBL4323343; CHEMBL1235932; ZINC4329335; G2F; 2-Fluoro-2-deoxy-beta-D-glucopyranose; beta-D-Glucopyranose, 2-deoxy-2-fluoro-; WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*F]/1/

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 5288324
ChEBI ID: CHEBI:49128
CAS Number: CAS 38711-37-4
TTD Drug ID: DMMC8IG

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Lactase-phlorizin hydrolase (LCT)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Alpha-D-Mannose	DMF5DLW	Discovery agent	N.A.	Investigative	[1]
Fucose	DMAHMSV	N. A.	N. A.	Investigative	[1]
Nojirimycine Tetrazole	DMYZRTB	Discovery agent	N.A.	Investigative	[2]
2,5-dideoxy-2,5-imino-D-altritol	DMI1O54	Discovery agent	N.A.	Investigative	[3]
Gluconolactone	DMO071E	Discovery agent	N.A.	Investigative	[2]
ETHYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE	DM0O4A2	Discovery agent	N.A.	Investigative	[2]
Hyacinthacine B3	DMJ9KNU	Discovery agent	N.A.	Investigative	[4]
D-Gluconhydroximo-1,5-Lactam	DM527XP	Discovery agent	N.A.	Investigative	[2]
2,5-dideoxy-2,5-imino-dl-glycero-D-manno-heptitol	DMKP7O0	Discovery agent	N.A.	Investigative	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Lactase-phlorizin hydrolase (LCT)	TTA0OSE	LPH_HUMAN	Inhibitor	[1]

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References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
3	2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease. Bioorg Med Chem. 2010 Jun 1;18(11):3790-4.
4	New polyhydroxylated pyrrolidine, piperidine, and pyrrolizidine alkaloids from Scilla sibirica. J Nat Prod. 2002 Dec;65(12):1875-81.
5	Nitrogen-containing furanose and pyranose analogues from Hyacinthus orientalis. J Nat Prod. 1998 May;61(5):625-8.