Details of the Drug-Related molecule(s) Interaction Atlas | DrugMAP

General Information of Drug (ID: DMMCJLH)

Drug Name	Malate Drug Info
Synonyms	Apple acid; Butanedioic acid, hydroxy-, (2S)-; J3TZF807X5; L(-)-Malic acid; L-(-)-Malic acid; L-2-Hydroxybutanedioic acid; L-Apple acid; L-Hydroxybutanedioic acid; L-Hydroxysuccinic acid; L-Malic acid; L-malate; Malic acid, L-; S-(-)-Malic acid; S-2-Hydroxybutanedioic acid; (-)-(S)-Malic acid; (-)-Hydroxysuccinic acid; (-)-L-Malic acid; (-)-Malic acid; (2S)-2-Hydroxybutanedioic acid; (S)-(-)-Hydroxysuccinic acid; (S)-2-hydroxysuccinic acid; (S)-Malic acid; (S)-malate; 97-67-6; MFCD00064213; NSC9232; UNII-J3TZF807X5
Cross-matching ID	PubChem CID 222656 ChEBI ID CHEBI:30797 CAS Number CAS 636-61-3 TTD Drug ID DMMCJLH INTEDE Drug ID DR2056

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
NADP-dependent malic enzyme (ME1)	DE97WM8	MAOX_HUMAN	Substrate	[1]
L-malate:NADP(+) oxidoreductase (maeB)	DEIRBUF	MAO2_ECOLI	Substrate	[2] , [3]

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References

1	Structural characteristics of the nonallosteric human cytosolic malic enzyme. Biochim Biophys Acta. 2014 Oct;1844(10):1773-83.
2	Thermostable, ammonium-activated malic enzyme of Clostridium thermocellum. Biochim Biophys Acta. 1981 Aug 13;660(2):251-5.
3	The correlation between Clostridium-difficile infection and human gut concentrations of Bacteroidetes phylum and clostridial species. Eur J Clin Microbiol Infect Dis. 2014 Mar;33(3):377-83.