Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMMF6UB)

Drug Name

GE-1170A Drug Info

Synonyms

Elongation factor Tu inhibitors (bacterial infection); LDI-028; LDK-733; Elongation factor Tu inhibitors (bacterial infection), Novartis

Indication

Disease Entry	ICD 11	Status	REF
Bacterial infection	1A00-1C4Z	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Staphylococcus Elongation factor Tu (Stap-coc tuf)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
NAI-acne	DM7P0WR	Acne vulgaris	ED80	Phase 2	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Staphylococcus Elongation factor Tu (Stap-coc tuf)	TTYQIFM	EFTU_STAAS	Inhibitor	[1]

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References

1	GE2270A-resistant mutations in elongation factor Tu allow productive aminoacyl-tRNA binding to EF-Tu.GTP.GE2270A complexes. J Mol Biol. 2000 Dec 15;304(5):995-1005.
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031008)